I answered this on the Transportation board, but to echo what PP says, you'd have to book separate flights so probably at least two layovers. We fly from Buffalo, and SWA would not even pair the flight segments together for us to book it. We would have had to book separate one way flights with either ample time in between or an overnight on the west coast like PP mentions. The only viable option for us was to fly from Buffalo to Chicago to San Jose (one of the CA airports), spend the night, and then fly out to HNL the next morning. It was too complicated and not any cheaper, so we didn't do it.
If you're willing to forego the points for comfort and convenience, the nonstop flight to HNL from Atlanta on Delta is awesome. We would definitely take this flight again for our next trip, regardless of the cost.