I do know that there are quite a number of cleaners and detergents used. If there are specific ones to be used to avoid an allergic reaction, you might want to call back and make that request. I have heard they wipe down everything including inside the drawers and change all linens vs. just the sheets but I'm not sure what the products would be. I always advise that I am travelling with a service dog and hope that will warrant a special cleaning after we check out, for which I always leave an extra tip. I wouldn't want someone with allergies to dander to be in the room we've vacated.---Kathy