All TPV rooms in the Tower are for the most part equal, but I'd vote for a high floor myself.
Also, if I had a choice - I'd rather not be on the Chef Mickey's side of the building due to restaurant noise that tends to float up. Although one could easily go their whole trip and be out of the room enough for this to not be a factor at all, so this isn't some 'major' consideration in my opinion - just an observation.
This crude map shows the floor plan (ignore the CL lounge label, that's only on the 12th floor). Perfect rooms for me would be xx34-xx48 - away from Chef Mickey's, close to the MK. But I wouldn't be upset if I had a room more on the Chef Mickey's side.
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A popular request is an odd numbered room. Odd numbered rooms let you lay in bed and see the MK, like below.
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