We stayed in WDW many times when our twins were in cribs. We made it work no matter which resort we stayed in. I don't remember exactly how we laid things out in each different resort, but it seems like one crib always fit near the curtains and the other crib more near the bathroom area. We always made sure to leave a walking path for getting up during the night (lol).
Have lots of fun
with your twins in Disney. I cherish all of our WDW trips, but our trips when the girls were babies were some of the most precious trips ever!