Hopefully, you'll get a local to reply. If you are talking about a weekday, I'd say avoid it like the plague! If it's a weekend, go for it.
Usually, we avoid I-95 north of Fredericksburg, VA. Too many times we've gotten caught in snarled traffic, either due to volume, construction, and/or accidents, etc. Interestingly enough, our chokepoint on a summer 2001 trip was in MD, between the DE state line and Baltimore! We decided to try I-95 from Philly south again! Think I'll stick with my end around route.
Sharon