I took two of my three kids by myself when we dropped DH off in Alabama to coach at a football camp a few summers ago.
DD was 13 and DS was 11 1/2 and we all LOVED it. We all want to go back. We were there for 3 days, stayed at the Omni Riverfront Hotel - it was beautiful and right across the street from the Riverwalk and last stop of the riverfront rail, which took us right along the river to the FQ area. It was so easy to get around!
We did a ghost tour, which was so fun and the tour guide was so interesting - there was no way we would have learned everything we did about the history of NOLA without doing that tour! We rode the light rail through the Garden District, but it was POURING rain, so it was hard to see and it was HOT in the cars since we needed to keep the windows up or get drenched.
The best part of our trip was going to MS Rau Antiques on Royal street - ask to see the "secret room", and don't be afraid to explore every inch of the store. There will be back rooms, and staircases, hallways, etc that look like customers shouldn't be entering, but you can! And if you do go - be sure to ask to see the secret room! It's a MUST.