I'd like to have a nomadic retirement. My husband and I differ on what that would look like - he'd like an RV for extended travels and our current house as our "home base", while I'd prefer something like a conversion van that could be used either for short-term camping or to get between hotels/cabins/whatever and selling off our current house for something smaller and more practical (we're in a 150 year old Victorian with all the bedrooms on the 2nd floor and the laundry in the basement - not exactly an idea setup for aging-in-place - and I really don't want to be cleaning and maintaining a 4-bedroom antique in my golden years). But it is far enough off right now that other than saving to fund it, there's really not a lot of sense in thinking about specifics. If my mother lives as long as my grandmother did, I may be spending my retirement caring for her. And if my husband's health starts to fail as young as his father's did, he might not live long enough to see me retire at all (he's 9 years older).
I suppose it depends on the market. My great-aunt is in an "active senior" complex that is pretty middle of the road for our area (nice library and craft room, daily organized activities, but no gym or pool) and is paying $2500 for a one-bedroom that includes basic utilities (she pays her own cable and internet), plus a housekeeping upcharge. That includes some things a hotel room wouldn't, like three meals a day and a full kitchen, but we've certainly joked about the fact that she could get a room at the chain hotel down the street from her complex for less.
There are two real differences that I think tip the scales in favor of the senior complex, though. First is the social element - my grandmother insisted on staying in her own home and that was very isolating for her as her health declined, even with neighbors that were friends and came over often. I can only imagine that would be worse in a hotel where your "neighbors" are people just passing through for a night or two. And second, most senior complexes, even those that serve a healthy population and do not offer assisted living/nursing care, have some level of experience with and training for medical emergencies. When my great-uncle had a stroke and stopped breathing, the staff at their facility knew how to do rescue breathing and did an excellent job keeping him going while waiting for EMS to arrive. I don't think your average Holiday Inn staff would have been as capable.