Well… Sometimes I look around and see this 2000sq.ft. house full of furniture, see 3 vehicles in the yard, and talk to the amazing young woman that DD has become and wonder, "How the heck did DH and I DO this??" LOL!
I spent 25 years doing scientific research, so I have been part of some interesting things that I consider accomplishments. For example, I developed an antibody that shows when a specific neuronal protein is activated. This doesn't sound like a big deal, but it's used by researchers who are working on nerve growth and direction, so it's pretty useful in research on nerve regeneration. We actually sold this antibody to a pharmaceutical house, and occasionally I get a royalty check (my former boss gets the big bucks, lol, my cut is pretty small… but still…). I also used to work for a company that was heavily involved in Alzheimer's research, and was part of the team that developed the first transgenic mouse for Alzheimer's. Research in AD was challenged by the fact that only humans develop AD, and it could only be accurately diagnosed at autopsy, so at the time there was no animal model for observation, testing, etc. We developed an a mouse model that expressed the same tangles and plaques as humans do in Alzheimer's. I'm not going to debate the ethics of animal models in research- but personally having lost a family member to AD, I think this was pretty significant. Now, I played a small role- IIRC there were 37 scientists in 4 facilities working on this project- but it's a small satisfaction that I think made a decent contribution to Alzheimer's research. I realize that both of these are small accomplishments in small areas, but it's nice when years of research pans out and is somewhat successful!