We live in Vegas, and usually make it in 3.5 hours to
Disneyland doing 75 most of the way (that is the speed limit!) We also do not stop along the way, the one time we did stop at the Barstow Train, it took us 4 hours. Still not bad!
DO NOT, I repeat, DO NOT if you can absolutely help it, travel on a SUnday or Friday. You are just asking for a 6-7 hour drive of what should be 3-4. Also do not plan on getting back into Anaheim during a rush hour. We either leave around 7 am, and that gets us there about 10:45. Or we do not leave until after 4 pm, so we are getting there after all rush hours. I would rather wait two more hours at home than spend it in stopped traffic.
A friend of mine left at 1pm once, which would get you into the main freeways about 5pm, and we left Vegas at 3pm. We got there about 10 minutes after her! Crazy, but that's how it works.
Sorry to go on and on, as the PP said, there is not much to see along the way, it is one of the more boring drives. Thank goodness it's quick though. It's a family joke about the world's tallest thermometer!! Have a great trip!
Andrea